2Mohamed Fawzi,1Eman Zaki Nossair, 1Eman Zaki Nossair, 2Mohamed Ali Bakry

1National Liver Institute, 2Faculty Of Medicine Cairo Unversity

Background(s):

Uterine fibroids are benign encapsulated uterine tumors disrupt the functions of the uterus causing many symptoms ranging from menorrhagia and dysmenorrhea to recurrent pregnancy loss, and infertility, and are the most common reason for hysterectomy in premenopausal women. Magnetic Resonance Imaging (MRI) guided High-intensity Focused Ultrasound (MR-HIFU) is a recent very low-pain to painless non-invasive procedure that has shown excellent therapeutic efficacy in treating uterine fibroids. Here we present the MRI findings of the first cohort of Egyptian women with uterine fibroids who underwent MR-HIFU.

Material(s) and Method(s):

Twenty Egyptian female patients in their reproductive age (18–45 years) with a total of 30 symptomatic uterine fibroids measuring between 3 – 12cms in diameter underwent MR-HIFU treatment in the National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt over a period of 9 months (Feb 2021 – Dec 2021). Fibroid size, T1 and T2 signal intensities and Funaki type and non-perfused volume (NPV) of uterine fibroids were recorded pre- and/or post-treatment. The mean fibroid volume change after 6 months was also noted. Also symptom relief was recorded.

Result(s):

Remarkably, all thirty fibroids showed no less than 70% non perfused volume in the contrast enhanced MRI performed directly after the session. Follow-up showed significant relief in the primary symptoms mainly bleeding and significant improvement in HG level and also follow-up size reduction was measured and showed at least 30 % decrease in size.

Conclusion(s):

TOur institution is the first to introduce the ground breaking technology of MR-HIFU in Egypt. We have shown high efficacy of MR-HIFU in the treatment of uterine fibroids in Egyptian women. Our results have great potential of the wider use of this minimally invasive and effective treatment of uterine fibroids not just in Egypt but all the Middle East and Africa.