1Ahmed Awad Bessar

1Zagazig University

Background(s):

To evaluate the efficacy of geniculate artery embolization (GAE) as a new method to alleviate intractable knee pain secondary to osteoarthritis (OA).

Material(s) and Method(s):

Twenty Egyptian female patients in their reproductive age (18–45 years) with a total of 30 symptomatic uterine fibroids measuring between 3 – 12cms in diameter underwent MR-HIFU treatment in the This is a clinical trial to assess role of GAE to treat OA related knee pain. In this perspective pilot study, twenty-three patients with moderate to severe knee pain and radiological findings of knee OA refractory to conventional medical treatment were enrolled. GAE was performed by antegrade femoral approach for the most painful knee by using 100 or 300-μm spherical particles. Assessment was performed at baseline and after GAE by 3 and 6 months. Radiological assessment was performed by magnetic resonant imaging and clinical assessment was performed by the Visual Analogue Scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).

Result(s):

RSuccessful embolization of at least one geniculate artery was achieved in all patients (100%). Mean VAS was improved from 81 mm ± 16 at baseline to 33 mm ± 10 at 6-month follow-up (P <.01). Mean WOMAC score improved from 65 ± 10 at baseline to 26 ± 20 at 6-month follow up (P < .01). Transient skin discoloration occurred in two of 23 patients (8.7%). Four of 23 patients (17.4%) developed transient sensory paresthesia in the leg of the treated side.

Conclusion(s):

GAE is a safe and hoping new technique for treatment of OA related knee pain. Further comparative studies are needed to determine long-term effect of GAE in comparison to other methods of treatment.